Endocrine Abstracts

Objective: The aim of this study is to evaluate the bone mineral density, hip geometry parameters and bone quality, measured by trabecular bone score (TBS) in patients with type 1 diabetes mellitus (T1DM).Materials and methods: We examined 97 patients with T1DM (28 males, 69 females, age: 31 (24.9−37.7) yrs., duration of DM: 11 (7−19.5) yrs., HbA1c: 8.6 (7.1−10) %, BMI: 23.1 (21.9−25.7) kg/m2). The control group consist...

Background and aims: Adipocytokines produced by adipose tissue cells, and their action is often systemic in nature. Connection of some adipocytokines (resisttin) with the development of autoimmune diseases such as type 1 diabetes (T1DM) is a perspective view. Therefore, the aim of study was to assess the association between adipocytokines (resisttin, adiponectin) and content of fat mass in T1DM.Materials and methods: Ninety-five patients with T1DM (60 wo...

Background and aims: According to the risk factors study for noncommunicable diseases STEPS 2016, carried out under the auspices of the World Health Organization, in 2016–17 years 60.6% Belarusians had overweight (BMI > 25 kg/m2); 25.4% had obese (BMI > 30 kg/m2), and the proportion of women with obesity (30.2%) was 1.5 times higher than men (20.2%). Thus, the project aim was to develop a methodology for group non-drug treatment of overweigh...

According to the current expert recommendations it is advisable to screen microvascular complications: diabetic peripheral polyneuropathy (DPN), diabetic retinopathy (DR), diabetic nephropathy (DN) in all patients with type 1 diabetes mellitus (T1D) and disease duration of 5 years. Therefore, the aim of the study was to assess the clinical and laboratory parameters of patients with type 1 diabetes at the age of 30−45 years with duration of the disease 5–15 years, ta...

According to WHO epidemiological data, there are more than 650 million obese people in the world, the medical and social significance of which is determined by the development and aggravation of insulin resistance. Accumulation of experience in the treatment of patients with COVID-19 infection has demonstrated that obesity and diabetes mellitus are important risk factors affecting the clinical severity of inflammatory disease - for impaired function of β-cells along with ...

Background: The recommended method of initial testing for MEN2A is either a single or multi-tiered analysis to detect RET mutations in exon 8, 10, 11, 13, 14, 15, and 16.The aim of the study was to determine the relationship between the aggressiveness of the clinical course of MTC and identified mutations.Materials and methods: The research is carried out of the program ‘To develop and implement effective technologies for the ...

According to modern concepts, stress hyperglycemia and diabetes mellitus (DM) are often found in hospitals and are associated with an increase in complications, length of hospitalization and mortality. The analysis of data on the COVID-19 pandemic indicates a worse prognosis and a high risk of hospital complications in patients with DM.Aim: The aim of the study was to evaluate clinical and laboratory parameters that can be used to predict an unfavorable ...

Both hyperglycemia and in-hospital hypoglycemia are associated with poor hospital outcomes and increased healthcare costs. The effect of hypoglycemia may be due to the severity of the infectious disease and the high incidence of comorbidity. The aim of the study was to study the possible relationship between the severity, duration and compensation of hyperglycemia with the course of Covid-19.Materials and methods: A retrospective analysi...

Objective: The introduction of imaging technologies into routine clinical practice has increased the pituitary incidentalomas cases detection by magnetic resonance imaging (MRI) of the brain. Identification of pituitary formations requires additional hormonal examination and dynamic MRI pituitary examination for differential diagnosis and treatment strategy for patients. An important clinical problem is to determine the malignancy, predictors of potential growth and hormonal a...

Background and aims: According to modern researchers, in patients with type 1 diabetes (T1D), the presence of diabetic osteopathy and an increasing fracture risk is evident. However, the determination of bone mineral density only is not enough to adequately assess the quality of the bone. Thus, the aim of the study was to study of the lumbar spine trabecular bone score as qualitative bone characteristic in T1DM men.Materials and methods: 52 males with T1...